Eventually, complete proof came from chromosome maps in Morgan's own lab.
2.
The Entrez system can provide views of gene and protein sequences and chromosome maps.
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Thus a record of the history of karyotype changes that have occurred during evolution have been attained through comparative chromosome maps.
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His work led to the development of chromosome maps of laboratory mice, a crucial step in identifying and analyzing the molecular defects often associated with cancer.
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BacMap also has a number of updated data browsing and text searching tools that allow filtering, sorting and more facile display of the chromosome maps and their contents.
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Rudolph Tanzi, a professor of neurology at Harvard Medical School, said the chromosome map could eventually shed light on why people with Down syndrome have a very low rate of breast, lung and gastrointestinal cancers.
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The task was daunting but not insuperable if the chromosomes could be broken down into smaller pieces for decoding and assembled through some kind of chromosome map that would show how the pieces fit together.
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Fluorescence " in situ " hybridization ( FISH ) with DNA clones ( YAC clones, cosmids ) allowed the construction of chromosome maps at a resolution of several megabases that could detect relatively small chromosome rearrangements.
9.
He also surmised that unequal crossing-over was possibly a main force of evolution . " Sturtevant . . . elaborated on these ideas by incorporating the conception of linear arrangement and by constructing the first chromosome map.